Knuckles make many things possible.

Detailed manual work, clever or beautiful depends on knuckles and knowing how to use them.

Referring to knuckles specifically usually refers to fighting with fists, or the unattractiveness of knuckes.

Knuckles are as much about beauty as about anything else. Many beautiful objects have been made with fingers that are in parts and go back and forth.

Many beautiful touches would not have been possible without knuckles, dearly beloved flexible and therefore baggy knuckles.